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Information × Registration Number 0221U103350, 0120U105409 , R & D reports Title Develop technology for the production of probiotics based on lacto- and bifidobacteria for the prevention and treatment of gastrointestinal diseases of farm animals and poultry popup.stage_title Head Palii Anatolii Р., Registration Date 18-02-2021 Organization National Scientific Center Institute of Experimental and Clinical Medicine popup.description2 The biological properties of Lactobacillus plantarum 7, L. delbrueckii 8, L. casei var. hamnosus 9, L. casei var. rhamnosus 14, L. plantarum 19, L. plantarum 22, L. casei 27, L. plantarum 7-317, Bifidobacterium bifidum 1, B. infantis 14, B. adolescentis 17, B. adolescentis 23, B. longum 23, B adolescentis 17-316, B. adolescentis 3 after 2, 3 and 4 years of storage. A "Standard Operating Procedure for Determining the Antagonistic Properties of Lactic Acid Bacteria" has been developed, which will facilitate the selection of lactic acid bacteria to create probiotic preparations to ensure epizootic well-being against dysbacteriosis in young farm animals. A method for culturing lactobacilli and bifidobacteria has been developed, which will promote the cultivation and storage of lactic acid bacteria to create probiotic preparations. The composition of the pharmaceutical composition in the form of capsules is proposed: dry biomass of Lactobacillus plantarum № 7-317 and Bifidobacterium adolectentis № 17-316 - 50%, glucose - 5%, lactose - 5%, Aerosil 200 - 9%, starch - 31%. The content of lyophilized bacteria in one capsule is not less than 1 X 107 CFU of bifidobacteria / cm3 and 1 X 107 CFU of lactobacilli / cm3. According to the results of the research, the technology of production of the encapsulated form of probiotic preparation was developed.  Product Description popup.authors Huzhvinska Svitlana O Dotsenko Kateryna A popup.nrat_date 2021-02-18 Close