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Information × Registration Number 0221U103461, 0118U005268 , R & D reports Title Intelligent biosensor systems for the detection of some metabolites for the control of social-significant human diseases development Section 3. Target synthesis of metal nanoparticles, composites and thin films to increase the efficacy of electrochemical biosensors popup.stage_title Head Rieznichenko Liudmyla S., Кандидат біологічних наук Registration Date 20-02-2021 Organization F. D. Ovcharenko Institute of Biocolloidal Chemistry NAS of Ukraine popup.description2  During the third stage of the project fulfillment it has been studied the catalytic activity of glucose oxidase in a model solution of glucose under the influence of synthesized gold and silver nanoparticles of different sizes; the nature of the influence of pH, temperature as well as nanoparticles’ concentration on these processes have been analyzed to determine the optimal conditions for designing the laboratory prototypes of electrochemical enzyme sensors using synthesized nanomaterials. The optimal concentration ratios for different types of nanomaterials, for which the formation of electroactive complexes of glucose oxidase with nanoparticles takes place, were determined. A new type of gold nanoparticles was synthesized using glucose oxidase as a reducing agent and stabilizer. Approaches to the immobilization of enzyme complexes with nanoparticles on the surface of laboratory prototypes of the developed electrodes have been experimentally investigated. Laboratory prototypes of planar electrodes with nanocomposite coating based on nanoparticles of metals, carbon and PVC matrix have been created. Product Description popup.authors Gruzina Tamara H Dybkova Svitlana M Rieznichenko Liudmyla S popup.nrat_date 2021-02-20 Close