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Information × Registration Number 0221U104079, 0119U102720 , R & D reports Title Controlled association of plasmonic nanoparticles in the presence of biomolecules as a method for creating sensor systems and theranostics popup.stage_title Head Mukha Yuliia P., Registration Date 02-03-2021 Organization Chuiko Institute of Surface Chemistry of NAS of Ukraine popup.description2  A combined spectroscopic and colorimetric study was performed concerning optical properties of noble metal nanoparticles (NPs), gold and silver, and their changes in the presence of biological markers of prostate cancer, namely polyamines (PA) - putrescine, spermine and spermidine. It is shown that the interaction of NPs with PA is accompanied by a change in the color of colloidal systems and a shift in the position of the localized surface plasmon resonance (LSPR) band maximum of metals in the absorption spectra for 100-160 nm in the long-wavelength region. It was shown that the change in the optical response was dependent on type and concentration of PA and varied between different types of NPs, that allows their selective determination. The finite-difference time domain (FDTD) method was proposed as a tool for modeling of spectra of nanoscale optical systems, which can approximate the processes occurring in real systems, such as the association (aggregation) of nanoparticles. Product Description popup.authors Gavryliuk Oleksandr O. Mukha Iuliia P. popup.nrat_date 2021-03-02 Close