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Information × Registration Number 0221U104395, 0118U001139 , R & D reports Title Biological and medical systemic factors for the development and course of coronary heart disease popup.stage_title Head Mintser Ozar P, Registration Date 17-03-2021 Organization PL Shupyk National University of Health of Ukraine popup.description2  Preliminary studies related to developing in silico models have been performed. The studies are aimed at determining the role of trigger reactions and trigger cascade effects in the occurrence of coronary heart disease and metabolic syndrome. The structure of multidimensional ontologies and the training courses universal builder for the systematization of data on coronary heart disease in the continuing professional development have been presented. The role of systemic miRNAs interactions in the pathogenesis of cardiovascular diseases has been substantiated. The role of spatial trigger waves in systems biology and systems medicine is conceptually generalized. There have been systematized the research on self-assembly process, leading to the functional tissue formation in a cell -type manner that does not require external energy. Prognostic models of the risk of developing ischemic disease based on integrative systemic biological approach have been investigated. The possibilities of personalized medicine for insurance medicine based on the use of systemic medicine have been evaluated. Product Description popup.authors popup.nrat_date 2021-03-17 Close