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Information × Registration Number 0221U104694, 0118U000843 , R & D reports Title Development of innovative and resource-saving technologies for the production of food additives and cosmetics, synthesis and study of the properties of new heterocyclic compounds popup.stage_title Head Saribiekova Diana H, Registration Date 06-04-2021 Organization Kherson National Technical University popup.description2  The effect of selected silicones, namely: cyclopentasiloxane, phenyltrimethicone and amidomethicone on the organoleptic and physicochemical characteristics of cosmetic emulsions was determined experimentally. It is established that the addition of selected silicones to the composition of the base emulsion in a concentration of 1 to 10% contributes to the improvement of physicochemical, organoleptic, rheological and sensory properties of the emulsion. According to the results for use, we can recommend the studied silicones in the following concentrations: amidomethicone - 2, 3, 5, 7%; cyclopentasiloxane - 5, 7, 10%; phenyltrimethicone - 5, 7 and 10%. In order to study the condensation processes for the formation of new heterocyclic structures, which are based on two biologically active heterocycles - pyrimidine and purine, simplified and effective methods for the synthesis of reactive bis-purinopyrimidines have been developed. On the example of condensations of starting purinopyrimidines with N-nucleophilic reagents, their reactivity with respect to two reaction centers - chlorine atom and ethoxycarbonyl. The structure of intermediate and final compounds is proved. High biological activity of the synthesized starting compounds was revealed. Product Description popup.authors popup.nrat_date 2021-04-06 Close