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Information × Registration Number 0221U104830, 0120U002187 , R & D reports Title To develop a method of treatment of patients with metastatic, progressive differentiated thyroid cancer, refractory to radioiodine. popup.stage_title Head Solodiannykova Oksana I., Registration Date 25-04-2021 Organization National Cancer Institute popup.description2  The object of the study - 38 patients with iodine-negative metastases of the thyroid gland. The aim of the work is to develop a method of treatment of iodine-negative metastases of differentiated thyroid cancer. Research methods and equipment - whole body scintigraphy with 99mTc-MIBI; whole body scintigraphy with 99mTc-DMCA; positron emission tomography with 18F-FDG; methods of statistical processing of results; two-detector gamma camera from Mediso (Hungary), single-photon emission computed tomography (SPECT) “E. CAM 180 ”. 38 patients with thyroid disease were examined, 10 of them treated with the targeted drug sorafenib, SVT with 99mTc-MIBI and 10 with 99mTc-DMCA to assess the therapeutic efficacy by scintigraphic imaging. A method of treatment with drugs, tyrosine kinase inhibitors, iodine-negative metastases of thyroid cancer has been developed. In 10 patients with thyroid and iodine-negative metastases, scintigraphic evaluation of the effectiveness of treatment with PET with 18F-FDG was performed. In 8 patients with bone lesions, treatment was performed with radionuclide and remote radiation therapy. The effectiveness of treatment was monitored using SVT with 99mTc-MDR. Product Description popup.authors Danylenko Victoria V. Dzhuzha Dmytro O. Kmetyuk Yaroslav V. Sukach Georgii H. popup.nrat_date 2021-04-25 Close