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Information × Registration Number 0221U104972, 0117U000406 , R & D reports Title Develop methods chemoradiotherapy patients with secondary (metastatic) cancer of the vagina using various sources of radiation popup.stage_title Head Ivankova Valentina S., Доктор медичних наук Registration Date 28-04-2021 Organization National Cancer Institute popup.description2 The subject of the study was 93 patients with secondary (metastatic) vaginal cancer. The aim of the work is to increase the effectiveness of radiotherapy for patients with secondary (metastatic) vaginal cancer by using optimal planning, conformal irradiation, high-energy brachytherapy (192Ir, 60Co) and cytostatic drugs. Physical dosimetry and calculations of the absorbed dose of 192Ir sources of high activity, methods and tests of dosimetric, mechanical and optical parameters of the radiotherapy device "Gamma Med plus IX" for contact PT are carried out. Methods of chemo-radiation treatment of patients with secondary (metastatic) vaginal cancer using cytostatic drugs (oral fluoropyrimidines, platinum drug) as radiomodifiers during conformal radiation therapy and high-energy (HDR) 60Co and 192Ir-brachytherapy have been developed. The stages of topometric training, planning of conformal irradiation and high-energy 60Co and 192Ir-brachytherapy of patients with secondary (metastatic) vaginal cancer are determined. The direct results of treatment were studied: the effectiveness and toxicity of the developed methods of chemo-radiation therapy of patients with secondary (metastatic) vaginal cancer using cytostatic drugs as radiomodifiers during conformal radiation therapy and high-energy 60Co and 192Ir-brachytherapy. Conduct a comparative analysis of the effectiveness of high-energy (HDR) 60Co and 192Ir-brachytherapy. Product Description popup.authors Bakay Olga А. Baranovska Lydia M. Galyas Oksana V. Paliy Maxim І. Skomorokhova Tetyana V. Khrulenko Tetyana V. popup.nrat_date 2021-04-28 Close