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Information × Registration Number 0221U105149, 0115U000240 , R & D reports Title Biochemical mechanisms of dуsmetabolic processes development under the influence of chemical factors of the environment popup.stage_title Head Nakonechna Oksana A., Доктор медичних наук Registration Date 07-06-2021 Organization Kharkiv National Medical University popup.description2  Under prolonged exposure of oxyethylated nanylphenols and polyesters in doses (1/10 and 1/100) DL50 reactive oxygen species formation of is observed, enhancement of free radical oxidation reactions of biosubstrates accompanied by depletion of antioxidant resources, disturbance of redox signaling and damage of macromolecules. The xenobiotic in dose 1/100 DL50 influence investigation is performed and and they have been proved to cause "signalling" indexe changes in the oxidant homepstasis and reserve abilities of rat organism, which is accompanied by actevation on adaptation reactions in first 20 days, their exertion till 50th day and failure after 50th day of toxification. Product Description popup.authors Androsov Yevgen D. Bachinskiy Ruslan Orestovich Bezrodnaya Anastasiya Vasyleva Irina Myhailivna Hoydina Valentyna S. Hopkalov Volodymyr G. Horbach Tetiana V. Denysenko Svitlana A. Zhukov Viktor I Martinova Svitlana Mikolaivna Onishchenko Anna I. Polikarpova Hanna Valeriivna Popova Lyudmyla Dmytrivna Popova Tamara M. Stetcenko Svitlana Olexandrivna Tkachenko Anton S. Yarmysh Natalia V. popup.nrat_date 2021-06-07 Close