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Information × Registration Number 0221U105174, 0118U007346 , R & D reports Title Functional characteristics of the spinal cord neurons and their changes under various pathologies and injuries. popup.stage_title Head Voitenko Nana V., Доктор біологічних наук Registration Date 09-06-2021 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description2  Lamina I spino-parabrachial neurons (SPNs) receive peripheral nociceptive input, process it and transmit to the supraspinal centres. Although responses of SPNs to cutaneous receptive field stimulations have been intensively studied, the mechanisms of signal processing in these neurons are poorly understood. Therefore, we used an ex-vivo spinal cord preparation to examine synaptic and cellular mechanisms determining specific input-output characteristics of the neurons. Here we have shown that different mechanisms of signal processing allow lamina I SPNs to play distinct roles in nociception. Product Description popup.authors Andrianov Yaroslav Ye. Bagatska Olena V. Galaidych Oleg V. Duzhyi Dmytro Ye. Zabenko Elizaveta Yu. Kolyada Yuriy M. Kostyuk Olga I. Kosyak Victoria V. Krasnyakova Margarita Ye. Mitruzaeva Valeria A. Medvyedyev Volodymyr V. Pivneva Tetyana А. Romanenko Serhiy V. Yatsenko Vasyl P. popup.nrat_date 2021-06-09 Close