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Information × Registration Number 0221U105681, 0113U007274 , R & D reports Title Cellular mechanisms of functional characteristics realization in mammalian central and peripheral neurones. popup.stage_title Head Veselovskyi Mykola S., Доктор біологічних наук Registration Date 09-08-2021 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description2 Electrophysiological mechanisms of modulating effects on synaptic transmission and changes in the intracellular concentration of calcium ions in the norm, under the conditions of the pathological states simulation and the application of neuroactive substances, have been investigated on specially designed model objects: co-cultures of synaptically linked neurons of different parts of the nervous system (the co-culture of the neurons of the spinal ganglia and the neurons of the dorsal horns of the spinal cord, of the trigeminal ganglion neurons, of the retinal ganglion cells and superficial superior colliculus neurons). Properties of calcium signals caused by neuronal activation and their changes in artificial diabetes, exitotoxic lesions and application of neuroprotective substances have been investigated on ganglion cells of the retina and cultured neurons of the hypocampus.  Product Description popup.authors Voytenko Serhiy V. Gotsulyak Yaroslav М. Grigorov Oleksiy O. Dumanska Hanna V. Kolesnyk Oksana P. Kuznetsov Kyrylo І. Martyniuk Natalia Ya. Maslov Vitaliy Yu. Purnyn Olena E. Remizov Igor M. Rikhalsky Oleg V. Telka Maria V. Fedulova Svitlana А. Shypshyna Mariia S. popup.nrat_date 2021-08-09 Close