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Information × Registration Number 0221U105952, 0120U104249 , R & D reports Title Advanced SERS-based nanoplatform for efficient detection of biomolecules and pathogens popup.stage_title Head Dzhagan Volodymyr M., Доктор фізико-математичних наук Registration Date 14-09-2021 Organization VE Lashkarev Institute of Semiconductor Physics of the National Academy of Sciences of Ukraine popup.description2  The design of SERS substrates with the morphology of inverted pyramids was developed and nanostructured SERS substrates based on polymer and silicon oxide were fabricated. The basic principles of modification of the obtained nanostructured surfaces by molecules (thiols) and metal ions in order to increase the efficiency of further selective addition of biomolecules, as well as methods of functionalization of modified surfaces by biomolecules (antibodies) are proposed. To achieve the maximum efficiency of SERS-substrates, their morphology was optimized, the optimal parameters of modification of the nanostructured substrate by linker molecules and its functionalization by biomolecules-analytes were determined. The efficiency of the manufactured SERS substrates is demonstrated in principle: with their help the SERS spectra of antibodies and other biomolecules, in particular a number of amino acids, are obtained. The results of the research are presented at 2 conferences. 2 scientific articles were published and 1 patent of Ukraine was obtained. Product Description popup.authors Isaeva Oksana F Borova Mariya M. Buziashvili Anastasiya Yu. Hreshchuk Oleksandr M. Kapush Olha A. Mazur Nazar V. Pirko Yaroslav V. Plohovska Svitlana G. Yukhymchuk Volodymyr Oleksandrovych popup.nrat_date 2021-09-14 Close