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Information × Registration Number 0221U106262, 0117U007494 , R & D reports Title Improvement of methods of prevention, diagnosis and treatment of diseases of the reproductive system of a woman using the latest medical and molecular genetic technologies. popup.stage_title Head Gladchuk Ihor , Доктор медичних наук Registration Date 19-11-2021 Organization Odessa National Medical University popup.description2  It is established that risk factors for hyperproliferative processes of the endometrium (GPE) are heredity, early menarche, late menopause, polycystic ovary syndrome, obesity, inflammatory diseases of the genitals, thyroid disease, hepatobiliary diseases, arterial hypertension, arterial hypertension, arterial hypertension, arterial hypertension, hypertension. Hypermethylation of DNA genes SFRP2, GHSR and TNFA in GPE e prognostic markers of endometrial cancer. There is a strong correlation between age over 50 years and abnormal DNA methylation of SFRP2, GHSR and TNFA genes. An algorithm for early diagnosis and prediction of uterine cancer in women with GPE has been developed, taking into account risk factors, sonographic criteria and molecular genetic markers. Product Description popup.authors Bichevska Rozaliia G Bykova Nataliia A Butakova Marianna A Volianska Alla H Hladchuk Ihor Z Zhelezov Dmytro M Zaporozhan Valerii М. Kucherenko Olena Yu Kushnir Galyna Yu Marichereda Valeriia H Posohova Svetlana P Rozhkovska Natalia M Chumal Zynaida V Shapoval Mykola V popup.nrat_date 2021-11-19 Close