Search academic texts

Information × Registration Number 0221U106394, 0116U008933 , R & D reports Title The pathophysiological mechanisms of the endothelial dysfunctions and hemostasis disorders at various pathophysiological conditions and also the pathogenetic substantiation of their correction. popup.stage_title Head Vastynov Ruslan S., Доктор медичних наук Registration Date 02-12-2021 Organization Odessa National Medical University popup.description2 Vascular endothelium by producing various biologically active substances plays an extremely important role in providing hemostatic reactions. Defect of the vascular wall is an important to the point determines the development of ongoing pathology, from risk factors to the occurrence of the pathological condition. Vascular endothelium is not only a target organ in the development of thrombosis, but also an effector in the pathogenesis of its complications. The obtained data indicate that 34 rats with model of chronic ischemia already during the 1st day of the experiment registered pronounced changes in motor and late behavior, muscle and coordination activity, as well as severe newrological disorders and emotional disorders. The comprehend sive pathogenetically sound pharmacological correction of motor behavior and emotional sphere will also be aimed at the formation of anti-ischemic effect.  Product Description popup.authors Vastyanov Rooslan S Kirchev Vladyslav V M’yastkivs’ka Ivanna V Ostapenko Ihor O Savitskyi Ivan V Sadovyi Oleksandr S Sarakhan Vasyl M Stoyanov Oleksandr M popup.nrat_date 2021-12-02 Close