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Information × Registration Number 0221U106711, 0118U001834 , R & D reports Title To study the clinical and biochemical and structural features of the formation of steatosis and liver fibrosis in patients with chronic diffuse liver diseases popup.stage_title Head Stepanov Yurii M, Registration Date 17-12-2021 Organization State institution institute of gastroenterology of nams of Ukraine popup.description2 The object of the study is steatosis and fibrosis in chronic diffuse liver disease (CDD) with various etiological factors. The aim of the study was to determine the relationships between clinical, biochemical and structural features, hormonal spectrum, immunocytokine status, small intestinal microbiota for the formation of steatosis and liver fibrosis in patients with chronic diffuse liver disease. Research methods - clinical, instrumental, morphological, biochemical, immunological, enzyme-linked immunosorbent assay, pathophysiological, statistical. The study found relationships between the severity of steatosis, liver fibrosis and metabolic, cytokine, hemodynamic, morphological parameters in the examined patients. Methods for the diagnosis of steatosis and liver fibrosis in patients with CDP have been developed. New data on the development of steatosis and liver fibrosis of alcoholic and toxic genesis in experimental models are obtained, approaches to inhibition of structural changes in the liver are substantiated.  Product Description popup.authors Haidar Yurii Adolfovych Galinskiy Oleksiy O. Grabovska Olena I Didenko Volodimir Izotovich Zigalo Elvira V. Karachinova Viktoria Anatoliivna Klenina Inna A. Konenko Irina S Melanich Svetlana Leonidovna Milostiva Dariya Fedorivna Petishko Oksana P Tatarchuk Oksana M. Yagmour Victoria B popup.nrat_date 2021-12-17 Close