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Information × Registration Number 0222U000836, 0120U100150 , R & D reports Title Stable carbenes of heterocyclic and acyclic series. Synthesis and physico-chemical properties popup.stage_title Head Korotkikh Mykola I., Доктор хімічних наук Registration Date 19-01-2022 Organization Institute of Physical and Organic Chemistry and Coal Chemistry. LM Litvinenko of the National Academy of Sciences of Ukraine popup.description2  Object of study. New stable nucleophilic carbenes and olefins, their precarbenic and carbenoid forms of mono-, di- and polynuclear type with steric protection of the carbene center for creation of highly effective catalysts of reductive dehalogenation reaction and other halogen substitution reactions of haloarenes. The aim of the work is the synthesis of new carbene complexes of silver and palladium for use in catalysis and in the search for new biologically active compounds, production of nucleophilic olefins with high electron donating ability, their precursors. Study of transformations of carbenes and nucleophilic olefins with electrophiles. Study of their physical and chemical properties. Research methods - synthetic, spectral (NMR spectroscopy), analytical (chromatographic, elemental analysis), computational (quantum chemical research). Research results: New types of complexes of highly basic carbenes and olefins were synthesized - imidazol-2-ylidenes with long-chain substituents, imidazolium-4-ides with sterically shielding groups, methyleneazolines with silver and palladium compounds. In situ reactions of methylene azolines and carbenes with phenyl isothiocyanate yielded azoline thioamide derivatives and zwitterionic compounds, and further functionalization reactions leading to carbonyl derivatives were performed. The philicity indices IeH, PpH were obtained by DFT method. Field of application - synthesis of stable carbenes and their carbenoid forms, catalysis of organic reactions. Product Description popup.authors Yenya Vasyl І. Gvozdetska Viktoriya O. Gresko Sergii V. Doroshenko Tatyana F. Kompanets Mikhaylо О. Konovkina Olga A. Korotkikh Vladislav M. Nechitailov Maxim М. Popov Anatolii F. Rayenko Gennady F. Ustilko Yuliya O. Shvaika Oleksii P. popup.nrat_date 2022-03-09 Close