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Information × Registration Number 0222U000858, 0119U100446 , R & D reports Title Improvement of approaches to diagnosis and prevention of occupational lumbar-sacral radiculopathy taking into account morphological and functional peculiarities of disease development popup.stage_title Head Lashko Oleg Mykolayovich, Registration Date 20-01-2022 Organization Kundiev Institute of Occupational Health of the National Academy of Medical Sciences of Ukraine popup.description2 Scientific research work is devoted to the topical problem of occupational medicine - improving the system of diagnosis and prevention of occupational chronic lumbosacral radiculopathy (CLSR) by studying the features of the clinical and functional state of the nervous and musculoskeletal systems and determining the level of vitamin D, macro- and microelements concentrations (MaE and ME) in biological environments at workers in the conditions of influence of considerable physical activity. The main signs of degenerative-dystrophic changes of the spine in the analysis of computed tomography and magnetic resonance imaging of patients with occupational CLSR identified osteochondrosis, spondyloarthritis, spondylolisthesis, spondylosis in above 90 % of examinated of all professions. It is established that the most informative indicators for determining impulse conduction disorders by nerve fibers in patients with occupational CLSR according to electroneuromyography are: decrease in the amplitude of the M-response when stimulated at the distal point and pulse velocity by long nerves of the lower extremities. It is proved that the value of T-score below -1 is an informative diagnostic indicator of the development of osteopenia, which was diagnosed in 20% of miners with occupational CLSR. By the method of assessing the 10-year risk of femoral fractures and other major osteoporotic fractures (FRAX) was revealed that the most significant changes in bone tissue are diagnosed in miners aged 50 to 59 years, in which the rate is 3.78 (p<0,05). Diagnostic risk criteria for the development of disorders of bone structure are: the concentration of vitamin D below 30 ng/ml (p <0,05), Ca - below 2,16 mmol/l (p<0,05), Mg - below 0,72 mmol/l (p<0.05), Al - above 3.3 μMol/l (p<0.05), B - below 62.90 μMol/l (p<0.05), P - above 3.2 mmol/l (p<0.05). Product Description popup.authors Basanets Angela Volodymyrivna Hvozdezkiy Viktor Anatoliyovych Lashko Oleg Mykolayovich Ostapenko Tetyana Anatoliyivna popup.nrat_date 2022-03-09 Close