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Information × Registration Number 0222U002440, 0121U107518 , R & D reports Title Effective methods for formation of 2-styrylpyrimidines based on 2-(2-hydroxy-2-arylethyl) -2,3-pyrimidin-4(3H)-ones popup.stage_title Head Yavolovskyi Arkadii А., Доктор хімічних наук Registration Date 13-02-2022 Organization Physico-Chemical Institute O. Bogatsky National Academy of Sciences of Ukraine popup.description2 Objects of research – 2-styrylpyrimidines, 2-(-hydroxyalkyl)-pyrimidin-4(3H)-ones, 2-(2-oxo-2-arylethylsulfanyl)-pyrimidin-4 (3H)-ones. The aim of work is to develop effective methods for synthesis 2-styrylpyrimidines based on 2-(-hydroxyalkyl) -pyrimidin-4(3H)-ones. Research methods and equipment: PMR-spectroscopy (Varian WXP-500), mass spectrometry (MX 1321). A preparative method for obtaining a number of 2-(-hydroxyalkyl) -pyrimidin-4(3H) -ones by reduction of 2-(2-oxo-2-arylethylidene)-2,3-dihydropyrimidine-4(1H)-ones has been developed. The possibility of desulfurization of 2-(2-oxo-2-arylethylsulfanyl)-pyrimidin-4(3H) -ones in acetic acid has been studied. The structure of first obtained compounds was established by NMR1H-spectroscopy and mass spectrometry.   Product Description popup.authors Ivanov Yuri E. Grishchuk Lydia V. Pluzhnyk-Gladyr Serhiy M. Stepanov Dmytro Ye Yavolovskyi Arkadii O. popup.nrat_date 2022-03-09 Close