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Information × Registration Number 0222U003485, 0120U102179 , R & D reports Title Methodology for production and use of organic synthesis intermediates based on catalytic processes involving industrial gases. popup.stage_title Head Riabukhin Serhii V., Доктор хімічних наук Registration Date 03-04-2022 Organization Taras Shevchenko National University of Kyiv popup.description2 Object of research: Catalysts and composites based on available non-toxic metals, low molecular weight organic intermediates, building blocks for the synthesis of substances with useful properties, industrial gases. The aim of the project is to establish the factors that determine the catalytic activity of graphene-based composites, graphene-like materials, 3d-metal compounds in the processes of hydrogenation, oxidation, carbonylation and carboxylation of organic compounds using CO and CO2, and CH activation of C1-C4 alkanes. their conversion into carboxylic and boronic acids; creation of effective catalysts for such processes and development of a methodology for carrying out these reactions that will meet the requirements of green chemistry; use of developed procedures for the synthesis of useful intermediates and building blocks for the needs of medical chemistry. Research methods: LCMS spectroscopy, gas GCMS spectroscopy, NMR spectroscopy on 1H, 13C, 19F, 2D NMR nuclei spectroscopy (NOESY, COSY, HMBC, HSQC), elemental, X-ray phase, X-ray diffraction analyzes, scanning electron and transmission electron microscopy. A preparatively convenient and scalable approach for two-stage methylation of α-methyl ketones using the catalytic hydrogenation reaction in the second stage. A technique using 1H and 31P NMR spectroscopy for routine rapid quality control of Phos Pd G3 precatalysts for their use in fine organic synthesis is proposed. A method for obtaining Co-containing graphene composites used as catalysts for hydrogenation of quinoline as a model substrate and its substituted derivatives has been developed and the conditions of catalytic hydrogenation in the presence of such composites have been optimized. The Re2S7 / C composite has been proposed as a catalyst for the hydrogenation of nitrogen and sulfur-containing heterocycles, for which an effective production method has been developed.  Product Description popup.authors Vyshyvana Iryna Н. Volochnyuk Dmitro M. Govorun Dmytro М. Grabchuk Galyna P. Kolotilov Serhiy V. Lyapunov Оlexander Yu. Makhankova Valeriya H. Nosyk Pavlo S. Ostapchuk Evgen M. Pashchenko Oleksandr Ye. Zyganova Ganna I. popup.nrat_date 2022-04-03 Close