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Information × Registration Number 0222U003712, 0119U000578 , R & D reports Title Optimize the comprehensive treatment of children with central nervous system embryonic tumors, tumors of the family of Yuinga sarcoma / primitive neuroectodermal tumors and high-risk neuroblastomas popup.stage_title Head Klymniuk Hryhorii I, Registration Date 25-05-2022 Organization National Cancer Institute popup.description2 The subjects are children with embryonic CNS tumors, Ewing's sarcoma / primitive neuroectodermal tumors and high-risk neuroblastomas. The aim of the research is to improve the treatment outcomes of children with embryonic CNS tumors, Ewing's sarcoma / primitive neuroectodermal tumors and high-risk neuroblastomas by optimizing comprehensive treatment. The following methods will be used to solve the tasks: clinical, radiation, morphological, immunohistochemical, molecular genetic, statistical. The overall survival of transplanted patients was 62.3% (NB) and 52.5% (SJ / PNEP), and non-transplant patients were 10% and 27.5%, respectively. The introduction of the technique of double VDHT with autoTSCPK increases the BRV of patients with high-risk neuroblastoma by 8.3%. The overall survival of patients with neuroblastoma who underwent 1 element of VDHT with autoTSKPK - 51.8%, BRV - 38.5%. The overall survival of patients with neuroblastoma who underwent double VDHT with autoTSCPK - 63.2%, BRV - 46.8%. (p = 0.02). Product Description popup.authors Pavlyk Serhiy V. Shaida Elen V. popup.nrat_date 2022-05-25 Close