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Information × Registration Number 0222U005012, 0121U107508 , R & D reports Title 620. Personalization of the treatment and development of new biologically active substances in optimization of pharmacotherapy of a few socially important diseases popup.stage_title Head Antonenko Petro В., д.мед.н. Registration Date 01-12-2022 Organization Odessa National Medical University popup.description2  The obtained data showed that at the beginning and at the end of inpatient treatment, the destruction processes and bacterial excretion more often observed in patients with the CYP3A4*AG genotype than in patients with the *AA genotype. Pulmonary tuberculosis patients with the *G mutant allele were somewhat more likely to have pulmonary tissue destruction both at the beginning and at the end of inpatient treatment, as well as a more widespread process of tuberculous infiltration of the lung tissue at the end of inpatient treatment, than patients with the *1/*1 genotype. The presence of the CYP3A4*1AG genotype, as well as the presence of the *G allele in tuberculosis patients can serve as a certain prognostic marker of a more severe course of pulmonary tuberculosis. Product Description popup.authors Al Nadavi Nora D. Antonenko Kateryna O. Antonenko Petro B. Kaprosh Antonina V. Kresyun Valentyn Yo. Lobashova Katerynа H. Matsegora Nina A. Ostapchuk Katerynа V. Poludenko Hanna O. Prystupa Bohdan V. Rozhkovsky Yaroslav V. Shemonayeva Katerynа F. Yunusova Saida I. popup.nrat_date 2022-12-01 Close