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Information × Registration Number 0222U005020, 0121U112939 , R & D reports Title Fulfillment of the tasks of the perspective plan of development of the scientific direction "Biology and health care" popup.stage_title Head Ostapchenko Liudmyla І., Доктор біологічних наук Registration Date 08-12-2022 Organization Taras Shevchenko National University of Kyiv popup.description2  In part 1 "Investigation of the state of regulatory systems at the cellular level in cases of specific pathologies to determine possible pharmacological targets" data on the state of regulatory systems in pathological cases and identified potential pharmacological targets have been accumulated and summarized. In part 2 "Study of the reactions of various organs and systems during the study of substances with pharmacological activity - in particular, changes in the level of the inflammatory state, degenerative processes in tissues, proliferative activity and carcinogenesis, angiogenesis" data collection was carried out on cytological and histological reactions in various organs and systems during studies of substances with pharmacological activity. In part 3 "Identification of factors that negatively affect the state of mental health in the conditions of the COVID-19 pandemic" a comprehensive psychological and psychiatric model for overcoming the negative consequences of the impact of the COVID-19 pandemic on mental health has been developed medical workers. In part 4 "Development of the methodology for obtaining and characterizing "hydrolyzed" peptides from hydrobionts as potential biotechnological products for the correction of metabolism" the methodology for obtaining and characterizing "hydrolyzed" peptides from hydrobionts as a potential biotechnological product for the correction of metabolism is developed. In part 5 "Investigation of the structural mechanisms of differential accuracy of DNA polymerases" the structural mechanisms of differential accuracy of DNA polymerases were investigated, as well as the structural mechanisms regulating the accuracy of biomolecular recognition were clarified. In part 6, "Investigation and modeling of molecular and cellular processes using bioimaging", a model of molecular and cellular processes was developed and information was collected on potential molecular mechanisms of the antitumor effect of antibiotics. Product Description popup.authors Andriichuk Olena M. Berehova Tetiana V. Vereshchaka Volodymyr V. Dragan Anatoliy I. Kalmykova Olesia O. Kondratiuk Tetiana O. Lukashovа Olga D. Myshakivska Olha М. Nuzhyna Nataliya V. Nuryshchenko Nataliia Ye. Raietska Yana B. Skivka Larysa M. Stepanova Lyudmila I. Tesʹolkina Tetyana S. Falalieieva Tetiana Mykhailivna Futurna Oksana А. Chumak Stanislav A. Shevchyk Vasyl L. Schkvyra Galyna O. popup.nrat_date 2022-12-08 Close