Search academic texts

Information × Registration Number 0222U005033, 0118U006190 , R & D reports Title Intellectual chemosensory systems for medical diagnostics of therapeutically important amino acids and their derivatives based on calixarene-containing compounds. Section 2. Molecular design and synthesis of highly selective calixarene receptors forming supramolecular complexes with amino acids and their derivatives popup.stage_title Head Kalchenko Vitalii I., Доктор хімічних наук Registration Date 08-12-2022 Organization Institute of Organic Chemistry NAS of Ukraine popup.description2  In order to create enantioselective sensors, capable of distinguishing D and L forms of biologically important amino acids and their derivatives, a preparative method of synthesis and separation into optically pure forms of N-(1-phenylethyl)amides of inherently chiral (cR)- and (cS)-dibenzoyloxycalix[4]arene acetic acids was developed. The absolute stereochemical configuration of each diastereomer was determined by X-ray structural analysis. It was shown that such compounds are convenient precursors for the synthesis of inherently chiral calix[4]arenes. Product Description popup.authors Yesypenko Olexandr Adolfovich Atamas Lyudmila Ivanivna Vishnevsky Sergii Grigorovich Dovgopyata Lidiya Soloveyivna Drapailo Andrii Bogdanovich Kalchenko Vitalii Ivanovich Rodik Roman Vasilovich Trybrat Olexandr Olexandrovich popup.nrat_date 2022-12-08 Close