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Information × Registration Number 0223U000017, 0121U107497 , R & D reports Title Analytical approaches and methodological explanation for studying the biopharmaceutical equivalence of generic drugs in comparative tests in vitro popup.stage_title Head Yegorova Alla V., Доктор хімічних наук Registration Date 01-01-2023 Organization Physico-Chemical Institute O. Bogatsky National Academy of Sciences of Ukraine popup.description2 The object of study - generic drugs "Bafazol ІС, tablets, 10 mg" and "SALUTEM IC, enteric-coated tablets, 500 mg" (manufacturer - SLC "INTERCHEM"). The subject of the study - spectrophotometric methods of quantitative determination of fabomotizole dihydrochloride for studying the dissolution profiles of the drug "BAFAZOL IC, tablets of 10 mg" and cation of ademethionine for studying the dissolution profiles of the drug "SALUTEM IC, enteric-coated tablets, 500 mg". Research methods - molecular absorption spectroscopy. The main idea of the work was to develop and validate spectrophotometric methods for quantification of released active pharmaceutical ingredients (API), to establish the biopharmaceutical equivalence of a number of home and foreign generic drugs in comparative in vitro tests (study of dissolution profiles).   Product Description popup.authors Yegorova Alla V. Aleksandrova Daria I. Leonenko Inna I. Scrypynets Yulia V. popup.nrat_date 2023-01-01 Close