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Information × Registration Number 0223U000269, 0122U000439 , R & D reports Title Synthesis and evaluation of antitumor activity of new heterocyclic and organophosphorus compounds popup.stage_title Head Vovk Andrii І., Registration Date 05-01-2023 Organization V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine popup.description2 Preparative methods for the synthesis of electron-deficient azoles were developed and primary studies of their antitumor activity were conducted. Condensed tricyclic systems based on pyrimidine-5-carbaldehydes were synthesized. Chiral synthetic blocks based on derivatives of 1,2-substituted aminoindanes and 1,2-substituted indanols were synthesized. An in silico evaluation of protein targets for bioactive derivatives of nitrogenous heterocycles was carried out. Product Description popup.authors Ivanova Irina V. Biletsky Igor І. Bagreeva Oksana S. Brovarets Volodymyr S. Brusnakov Mykhailo Yu. Buldenko Vladyslav M. Vaskevych Alla I Velihina Yeheniia S. Verves Evgeniy V. Vydzhak Roman M. Gayevsky Anatoly P. Herasymov Yehor S. Golovchenko Oleksandr V. Grishkun Evgeny V. Hushcha Tatiana О. Didiv Nataliya D. Demydchuk Bogdan A. Zhirnov Viktor V. Zinchenko Hanna M. Zyabrev Volodymyr S. Kibirev Volodymyr K. Kachaeva Maryna V. Kachkovskyi Oleksiy D. Кlyuchko Svitlana V. Kobzar Oleksandr L. Kozachenko Olexandr P. Kolodiazhna Anastasiia O. Kolodiazhna Olga O. Kolodiazhnyi Oleg I. Kondratyuk Kostyantyn M. Konovalenko Artem S. Kucher Oleksandr V. Losʹ Oleksandr V. Mityukhin Оleg P. Mischenko Iryna M. Merzhievskiy Danylo O. Mykula Mariya S. Moskvina Viktoria S. Mrug Galyna P. Muzychka Lyubov V. Muzychka Oxana V. Osadchuk Tetiana V. Pilyo Stepan G. Panchyshyn Svitlana Ya. Porhun Svitlana V. Potikha Lyudmyla M. Prysiazhniuk Dmytro V. Prokopenko Volodumir M. Prostota Yaroslav O Rentsevych Тetiana L. Severin Oleksandr O. Synenko Vitaliy O. Slastennikova Alyona O. Slyvchuk Serhiy R. Smolii Oleh B. Solomyanyi Roman M. Sukhoveev Olexandr V. Tanchuk Vsevolod Yu. Tatarchuk Alʹona V. Fedorenko Оlena А. Frasinyuk Mykhaylo S Tsygankova Vyktorya A. Charochkina Larysa L. Chumachenko Svitlana A. Shablykin Оleg V. Shablykina Olga V. Shejko Sergij Yu. Shulga Yuriy V. Yaremchuk Iryna О. popup.nrat_date 2023-01-05 Close