Search academic texts

Registration Number

0223U000377, 0121U112054 , R & D reports

Title

The development of methods for the prevention and intensive therapy of complications during complex treatment in cancer patients who have been infected by COVID-19.

popup.stage_title

Head

Krasnoselskyi Mykola V., Доктор медичних наук
Krutko Yevgen M., д.мед.н.

Registration Date

06-01-2023

Organization

State Organization "Grigoriev Institute for Medical Radiologiy and Oncology of the National Academy of Medical Sciences of Ukraine"

popup.description2

Object of study: cancer patients who have suffered COVID-19 in the process of special treatment. Purpose: to increase the effectiveness of complex treatment of cancer patients who have undergone COVID-19 by improving methods of prevention and intensive care based on the study of metabolic and energy features. Research methods and equipment: clinical-instrumental, biochemical, clinical, statistical; analyzers biochemical, immunochemical hematological; spirographic complex "Spirocom", diagnostic complex Spectrum +. Theoretical and practical results: metabolic disorders of organs and systems were found in 89.8% of cancer patients who had COVID-19. The highest frequency of development was on the 3rd-9th day after the disease. Systemic complications in patients with COVID-19 have been identified: respiratory damage in 89,2% of cases, cardiac complications in 63,1%, cerebral in 53,7%, urinary and digestive systems in 41,2% and 37,2%, respectively. Novelty: for the first time it was proved that in COVID-19 the immune system participated in the formation of an adaptive response, at the beginning of the disease (2-5 days) the phenomena of an overactive response were observed, followed by a hypoactive immune response (8-10 days), and as a consequence the development of a systemic inflammatory response syndrome, the generalization of which was realized by activated immunocompetent cells. Field of application: oncology, anesthesiology, intensive care.

Product Description

popup.authors

Volkova Yuliia Viktorivna
Mykhnevych Kostiantyn Georgievich
Pavlichenko Yuliana Valeriivna
Pylypenko Serhii Oleksandrovych
Revenkova Svitlana Ivanivna
Sorochan Pavlo Pavlovych

popup.nrat_date

2023-01-06