Search academic texts

Information × Registration Number 0223U000449, 0119U103864 , R & D reports Title Development of medical technologies for the diagnosis, prevention and treatment of resistant primary and secondary dyslipidemias popup.stage_title Head Mitchenko Olena I., Доктор медичних наук Registration Date 07-01-2023 Organization State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine" popup.description2  The object of the study is patients with suspected familial hypercholesterolemia (GH), high cardiovascular risk (CHD), hypothyroidism, diabetes mellitus (DM), obesity. The purpose of the work: Development of a step-by-step algorithm for the detection and differential diagnosis of satinotherapy-resistant primary (genetically determined familial hypercholesterolemia) and secondary dyslipidemias (on the background of comorbid pathology: diabetes, pre-diabetes, hypothyroidism, and obesity) to optimize the treatment of patients with high and very high cardiovascular risk Research methods and equipment. Anthropometric; Ultrasound of the heart, examination of the intima-media complex was carried out on an ultrasound device JE -33 No. BOCOHY of the Philips Ultrasound company, USA. The levels of hormones of the pituitary-thyroid axis were determined by the immunochemiluminescence method, the fasting insulin levels by the immunoenzymatic method ("DRG Diagnostic" kit, Germany). The formation of the Ukrainian registry of SG on the basis of the network of regional lipid centers as a national fragment of the International ScreenProFH registry and the European EAS-FH SC program with the involvement of regional lipid centers in Ukraine has been continued. Approaches are being implemented to optimize detection and differential diagnosis of patients with "possible" familial hypercholesterolemia for prevention, individualized and pathogenetically based treatment of high and very high risk patients. Product Description popup.authors Havrylenko Tetiana Illivna Ponomariova Galina V. Timokhova Kateryna Oleksandrivna Tretyak Iryna Mykhailivna popup.nrat_date 2023-01-07 Close