Search academic texts

Registration Number

0223U000781, 0122U000234 , R & D reports

Title

Improvement of patient-oriented approaches to the management of patients with cardiovascular and cerebrovascular diseases with comorbid conditions, in particular in those suffered from COVID-19

popup.stage_title

Head

Kravchenko Anatolii M., Доктор медичних наук

Registration Date

20-01-2023

Organization

State Institution of Science "Research and Practical Center of Preventive and Clinical Medicine" State Administrative Department

popup.description2

 Scientific project report: 224 pages, 23 tables, 13 figures, 2 supplements, 462 references. Key words: ARTERIAL HYPERTENSION, CORONARY HEART DISEASE, CORONAVIRUS DISEASE (COVID-19), POST-COVID SYNDROME, PATIENT-ORIENTED MEDICAL CARE, COMORBIDITY, DYSCIRCULATORY ENCEPHALOPATHY. The object of the study: arterial hypertension (AH), coronary heart disease (CHD), in particular with comorbidities, dyscirculatory encephalopathy, coronavirus disease (COVID-19), post-COVID syndrome. The aim of the study: to improve the management of patients with AH, CHD and cerebrovascular disorders, combined with the certain comorbidities and consequences of COVID-19 pandemic, by the implementation of patient-centered approaches to their prevention and treatment. The methods: bibliosemantic, systems analysis, clinical, laboratory, instrumental, survey, statistical. The data from 547 patients and 63 controls were analyzed. For the first time, we carried out an analysis of the attitude of CHD patients with comorbid conditions regarding the implementation of patient-centered care in clinical practice. We determined the interest and readiness of the majority of surveyed CHD patients to use the basic principles of patient-centered care. We analyzed the certain theoretical and practical aspects of the management of patients with AH, CHD and cerebrovascular diseases, in particular accounting for the state of autonomic regulation, functional state of the endothelium and thyroid gland, blood pressure variability, the presence of hematological malignancies, as well in those suffered from the coronavirus disease (COVID-19). We presented the evidence of the comorbidity as an important risk factor for the development of post-COVID syndrome, regardless the severity of acute SARS-CoV-2 infection. We proposed to use of a combination of edaravone, L-arginine/L-carnitine and xylitol-containing electrolyte solution as a method pharmacological treatment of patients with post-COVID conditions.

Product Description

popup.authors

Benkovska Lesia K.
Hidzynska Iryna M.
Kovalenko Olga Ye.
Kostiukevych Oksana M.
Litvin Olena V.
Mikhaliev Kyrylo O.
Matsyshyn Victor S.
Moroz Galina Z.
Netyazhenko Vasyl Z.
Ovodyuk Natalia M.
Pasko Victoria S.
Pryplavko Nataliia M.
Stelmakh Olga A.
Chernii Tetiana V.

popup.nrat_date

2023-01-20