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Information × Registration Number 0223U000945, 0119U002287 , R & D reports Title Analyses of reproductive potential of Lviv region of Ukraine population considering women's somatic and gynecologic health and impact of genetic factors in fertility disorders and pregnancy complications. popup.stage_title Head Registration Date 22-01-2023 Organization State Institution "Institute of Hereditary Pathology, National Academy of Medical Sciences of Ukraine" popup.description2 Maternal and fetal factors of perinatal complications in high-risk women in Lviv region were determined. It has been established that women at risk of perinatal pathology often have difficult termination of pregnancy, premature birth with complications and surgical delivery. Newborn babies from these mothers are often born prematurely, have a disturbed condition at birth, which requires additional measures by the obstetric service. The presence of the MTHFR 677T allele, the heterozygous genotype MTHFR 677ST and the homozygous genotype MTHFR 677TT in the female genome doubles the risk of congenital malformations of the cardiovascular system in the fetus. An algorithm for predicting the risk of perinatal pathology for young pregnant women, women with menstrual disorders, history of infertility, with extragenital pathology (diabetes, urinary tract disease, thyroid pathology), with the risk of congenital and hereditary pathology. Product Description popup.authors Korinec Yaroslav Malanchuk Oleksandra Melenchuk Lidiia Nechay Oksana Samokhvalova Anna Khobotna Ivanna Chorna Lilya Sharhorodska Yevgeniya Shkolnyk Olena Shlemkevych Artur popup.nrat_date 2023-01-22 Close