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Information × Registration Number 0223U001335, 0121U108468 , R & D reports Title Study of the spread of leptospirosis in animals and improvement of the system for diagnosis and prevention of the disease popup.stage_title Head Sytiuk Mykola Petrovych, Доктор ветеринарних наук Registration Date 27-01-2023 Organization Institute of Veterinary Medicine of the National Academy of Agrarian Sciences of Ukraine popup.description2  The inhibitory effect of green algae secretions (Hydrodiction reticulata, Enteromorpha enteromorpha, Cladophora collectiva) on the cultures of pathogenic leptospira has been experimentally proven. A strong degree of inhibition from intestinal enteromorph secretions was observed in populations of L. grippotyphosa (with an inhibition rate of 62.9±3.6%), L. polonica (52.5±1.8%) and L. canicola (66.7±3 .1 %). A moderate degree of inhibition of the Leptospira population was achieved by the isolation of all three types of algae: enteromorpha intestinalis - in cultures of the L. pomona serotype (inhibition 41.4±2.3%); cladophora is collected in cultures of serotypes L. tarassovi (30.2±2.7%) and L. polonica (47.7±1.2%), hydrodiction reticulate in cultures of serotypes L. grippotyphosa (31.1±1.3% ), L. icterohaemorrhagiae (43.5±3.4%) and L. tarassovi (33.3±2.1%). A weak degree of suppression was carried out by the isolation of intestinal enteromorphs on the population of pathogenic leptospira of the L. kabura serotype (24.8±3.7%), cladophores of the collective and reticulate hydrodiction on the population of L. canicola (19.8±3.2% and 14.2± 1.5%). Cultures of leptospira serotype L. Icterohaemorrhagiae were resistant to enteromorph intestinal secretions; collective cladophores - L. grippotyphosa, L. kabura and L. pomona; hydrodiction of reticulate - L. polonica and L. kabura. The inhibition of the growth of pathogenic leptospires from the release of cyanobacteria in a dilution of 1:10 was determined. The distribution of the effect of cyanide on leptospires was as follows: after 24 hours, inhibition of 50%, after 48 hours - 16.6%, after 72 hours - 6.7%, after 96 hours - 3.3% compared to the control. Product Description popup.authors popup.nrat_date 2023-01-27 Close