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Information × Registration Number 0223U001488, 0120U100722 , R & D reports Title Investigation of new synthetic polyphenolic compounds with antimicrobial properties for further application in the development of new drugs popup.stage_title Head Osolodchenko Tetiana P., Registration Date 28-01-2023 Organization State Institution "I.Mechnikov Institute of Microbiology and Immunology National Academy of Medical Sciences of Ukraine" popup.description2  The subject of the research is 74 samples of thick extracts of polyphenols from vegetable raw materials, and 315 samples of modified flavonoids (quercetin) and their combinations with amino acids. Research materials - 36 museum strains of pathogenic microorganisms and opportunistic patogens. Research methods- microbiological, mathematical, and statistical. The primary microbiological screening polyphenols extracted from plant raw materials and their modified derivatives toward expanded spectrum of bacterial strains reveals substances with high or moderate activity against gram-positive and gram-negative microorganisms. Promising results was obtained for succinylated quercetin derivatives, additionally modified with amino acids lysine and arginine. Product Description popup.authors Andrejeva Iryna D. Zavada Nadiia P. Lukjanenko Tetyana Riabova Iryna S. popup.nrat_date 2023-01-28 Close