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Information × Registration Number 0223U001498, 0120U100731 , R & D reports Title Current trends of measles spread in the North-Eastern region of Ukraine popup.stage_title Head Kalinichenko Svitlana V., Registration Date 30-01-2023 Organization State Institution "I.Mechnikov Institute of Microbiology and Immunology National Academy of Medical Sciences of Ukraine" popup.description2  Genetic relationships and evolutionary distances between closely related strains of measles virus genotypes B3 and D8 were analyzed. Genealogical trees of phylogenetic sequences of closely related strains of genotypes B3 and D8 circulating in the North-Eastern region of Ukraine were constructed using the latest version of the MADx program (MEGA X 10). Characteristic endemicity of individual strains of the measles virus in the North-Eastern region of Ukraine was revealed, which is of great importance for the study of transmission routes and improvement of measures of epidemiological surveillance of the incidence of measles. According to the results of a retrospective analysis for the period 2017-2022, it was determined that in the Kharkiv region during 2017-2019 there was an increase in the incidence of cowpox infection (2017 - 72%, 2018 - 75%, 2019 - 80.7%), primarily at the expense of unvaccinated persons (including those with unknown vaccination status) and persons with incomplete vaccination (one vaccination). To assess the state of specific measles immunity, 1,267 people aged 16 to 75 (adolescents, students, teachers, medical workers) were examined. It was determined that protective titers of antibodies had 87.3% of high school students, 78.2% of students in the last years of institutes, 82.2% of adults aged 30-39 years, 47.3% of adults aged 40-49 years, 44.6% of adults aged 50-59 years old and 42.0% of adults over 60 years old). This shows the urgent need to solve issues related to the introduction of additional immunization among the adult population of our country Product Description popup.authors Antusheva Tetyana I. Melentieva Christina V. Moiseienko Tetiana M. Ovetchin Petro Torianyk Inna I. popup.nrat_date 2023-01-30 Close