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Information × Registration Number 0223U002190, 0120U105603 , R & D reports Title To study the peculiarities of dysfunctional state of adipose tissue that form the metastatic potential and determine the tumor progressing popup.stage_title Head Hanusevych Iryna I., Доктор біологічних наук Registration Date 12-02-2023 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine popup.description2 Іn overweight patients with colorectal cancer, stomach cancer and breast cancer, significant changes in the redox state of peripheral blood associated with mitochondrial dysfunction of adipose tissue and tumor aggressiveness were found. Indicators associated with the metastatic potential of the tumor were identified, which are promising for their further study as markers for predicting the course of the tumor process in the presence of excess weight in patients: the rate of generation of superoxide radicals and the matrix metalloproteinases-2 and -9 activity of platelets, the ratio of platelets/lymphocytes, RNase and ODC activity in blood plasma. Product Description popup.authors Bubnovskaya Larysa M. Burlaka Anatoly Р. Virko Sergij V. Verbinenko Alla V. Galieieva Anastasiia M. Goncharenko Anton I Samoilenko Helena A. Chernobay Victor A. Shlyakhovenko Volodymyr O. popup.nrat_date 2023-02-12 Close