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Information × Registration Number 0223U002364, 0120U103612 , R & D reports Title The study of the activity of hemolytic processes in patients with diffuse large B-cell lymphoma of varying degrees of aggressiveness popup.stage_title Head Sivkovich Svitlana O., Доктор медичних наук Registration Date 15-02-2023 Organization State Institution "Institute of Hematology and Transfusiology of the National Academy of Medical Sciences of Ukraine" popup.description2  Object: 31 patients with diffuse large B-cell lymphoma of varying degrees of aggressiveness, erythrocytes and blood serum of patients with diffuse large B-cell lymphoma. Methods: generally clinical, immunohematological, biochemical, statistical. All patients with diffuse large B-cell lymphoma had destructive changes in the glycerophospholipids of the erythrocytes cell membrane and disruption of its functional activity. Patients with identified biomarkers BCL-2, BCL-6 and C-MYC had a one-step decrease in the minimum osmotic resistance of erythrocytes. Autoimmune anti-erythrocyte IgG thermal agglutinins and thermal acid hemolysins were detected at the IA stage of the disease, a complementary type of reaction was observed with the progression of the disease. Medical and social effect. Medicine. Product Description popup.authors Myronenko Galina A. Sivkovych Svitlana Oleksiivna Sergutina Svitlana Yu. Tymoshenko Uliana V. popup.nrat_date 2023-02-15 Close