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Information × Registration Number 0223U002379, 0121U107518 , R & D reports Title Effective methods for formation of 2-styrylpyrimidines based on 2-(2-hydroxy-2-arylethyl) -2,3-pyrimidin-4(3H)-ones popup.stage_title Head Yavolovskyi Arkadii А., Доктор хімічних наук Registration Date 16-02-2023 Organization Physico-Chemical Institute O. Bogatsky National Academy of Sciences of Ukraine popup.description2 The report is on 21 pages, consists 1 section, contains 1 table, 13 diagrams, 1 figure, and 22 references. The objects of research are 2-styrylpyrimidines, 2-(ß-hydroxyalkyl)-pyrimidin-4(3H)-ones, 2-(2-oxo-2-arylethylsulfanyl)-pyrimidin-4(3H)-ones. The aim of work is develop effective methods for synthesis 2-styrylpyrimidines, starting from 2-(ß-hydroxyalkyl)-pyrimidin-4(3H)-ones. Research methods and equipment: PMR spectroscopy (Varian WXP-500), mass spectrometry (MH 1321). A preparative method for obtaining compounds a series of (E)-6-R-2-styrylpyrimidin-(4H)-ones by dehydration of 2-(2-hydroxy-2-arylethyl)pyrimidin-4(3H)-ones in orthophosphoric acid at elevated temperature was developed. The structure of obtained compounds was determined using HNMR spectroscopy and mass spectrometry.   Product Description popup.authors Ivanov Yuri E. Grishchuk Lydia V. Pluzhnyk-Gladyr Serhiy M. Stepanov Dmytro Ye Yavolovskyi Arkadii А. popup.nrat_date 2023-02-16 Close