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Information × Registration Number 0223U002545, 0118U001192 , R & D reports Title Development, substantiation and implementation of new methods of prevention and treatment of trophic and purulent-necrotic complications of diseases of the lower extremities of vascular genesis using physical factors popup.stage_title Head Iftodiy Adrian Georgiyovych, Registration Date 23-02-2023 Organization Bukovinian State Medical University popup.description2  The analysis of surgical treatment of patients with atherosclerotic lesions of the arteries is presented. Revascularization of the lower extremities contributed to the growth of the index of the ratio of neutrophils and lymphocytes - by 29.4% (р<0.05), the index of the ratio of neutrophils and monocytes - by 5.8%, and the leukocyte index – by 17.97% (р<0. 05). Preoperative preparation reduces the level of endothelial dysfunction. In particular, before surgery, the content of CEC in the blood decreased by 17.99% (p<0.05), P-selectin – by 18.97% (p<0.05), endothelin-1 – by 15.62% (p<0.05), the level of NO – by 13.92%. Revascularization promotes an increase in the level of endothelial dysfunction due to an increase in the content of CEC, P-selectin, Endothelin-1 in the blood, respectively, by 2.3 (p<0.001) times, by 1.1 (p>0.05) times, by 1.7 (p<0.001) times. A staged approach to the surgical treatment of associated occlusive-stenotic lesions of the arteries made it possible to reduce the frequency of reperfusion complications to 18.6% of observations and achieve good results in 83.9% of patients. Product Description popup.authors Hrebeniuk Volodymyr Ivanovych Hrodetskyi Valentyn Korneliiovych Kozlovska Iryna Mykhajlivna Kolotylo Olexandr Bogdanovych Kulachek Iaroslav Vyacheslavovich Moskaliuk Oleksandr Petrovich Reva Volodymyr Borysovych Rusak Oleg Bogdanovich Fundiur Volodymyr Dmytrovych Shkvarkovskyi Igor Volodimirovich Yakobchuk Svitlana Oleksandrivna popup.nrat_date 2023-02-23 Close