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Information × Registration Number 0223U003358, 0118U007351 , R & D reports Title Ion channels - receptors of physical and chemical cues in regulation of excitation-contraction of visceral muscles in norm and pathology popup.stage_title Head Shuba Yaroslav М., Доктор біологічних наук Registration Date 20-04-2023 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description2  Our studies showed that: the TRPV1 channel in myocytes of detrusor smooth muscles of rats is localized on the membrane of the sarcoplasmic reticulum and can function as ionotropic receptors of lipid secondary intracellular mediators and mobilize Ca2+ ions from the sarcoplasmic reticulum of myocytes in response to cholinergic stimulation; the mechanism of mediated calcium-dependent inhibition of ATP-sensitive K+-channels of the SMC membrane of the detrusor of the rat urinary bladder during selective activation of the mechanosensitive Piezo1 channel was revealed. Product Description popup.authors Yelyashov Semen I. Kravchuk Danylo I. Kravchuk Lev I. Kuliyeva Yevheniya M. Sotkis Anna V. Filipov Igor B. Shuba Yaroslav М. popup.nrat_date 2023-04-20 Close