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Information × Registration Number 0223U004663, 0119U101458 , R & D reports Title The introduction of new methodological approaches to the development and studing of hybrid nanomaterials for medical purposes popup.stage_title Head Sukhodub Leonid F., Доктор фізико-математичних наук Registration Date 29-11-2023 Organization Sumy State University popup.description2  The object of the research is implementation of new methodological approaches to the development and study of hydric nanomaterials for medical purposes; morphological, structural and antimicrobial features of biodegradable materials and coatings; kinetics of drug release in vitro into a model environment. The purpose of the work is to develop methodical approaches to the formation of apatite-polymer biodegradable composite materials and coatings, their modification with bioactive inorganic substances and drugs (ZnO, ZnS, fullerene C60, anesthesin, sodium diclofenac) Optimization of the technology for obtaining biocompatible granular materials based on hydroxyapatite and the natural polymer chitosan as a system for prolonged delivery of drugs to the implantation zone was carried out; the method of synthesis of ZnS and ZnS-Alg nanostructured powders was optimized and the technology of applying ZnS and ZnS-Alg coatings on model titanium implants was developed; developed a technique for applying hybrid calcium phosphate coatings doped with silver ions and carbon nanoparticles to Ti6Al4V substrates. The sorption-drainage properties of the apatite-polymer composite were investigated. It has been proven that the use of a composite containing HA, chitosan and ZnO is effective for draining purulent cavities Product Description popup.authors Sukhodub Leonid F. popup.nrat_date 2023-11-29 Close