Search academic texts

Information × Registration Number 0223U005823, 0122U002131 , R & D reports Title Development of a biosensor system for monitoring ALT and AST in patients with liver and heart disease popup.stage_title Head Soldatkin Oleksandr O., Доктор біологічних наук Registration Date 31-12-2023 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2  In the course of the work, the reproducibility of continuous operation during one day, operational stability during a week of operation, and stability during storage in various conditions were studied for both monosensors and the biosensor system for determining ALT, AST and their ratio. The selectivity of the developed biosensing system with respect to electroactive substances that may be present in real samples was checked. The cross-effect of substrates and products of all enzymes involved in the work of the biosensor system was also investigated, and the prospective use of this system in the analysis of ALT and AST content in real samples was proven. A biosensory analysis of human blood serum samples was carried out for the content of AST and ALT in them. The standard traditional spectrophotometric technique was used as a control of the results of the biosensor activity analysis. Product Description popup.authors Bahmat Veronika A. Berketa Kseniia O. Kucherenko Ivan S. Kucherenko Daria Yu. Mruga Daryna O. Saiapina Olha Ya. Sobolevskyi Maksim popup.nrat_date 2023-12-31 Close