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Information × Registration Number 0224U000480, 0120U104590 , R & D reports Title To study the mechanisms of the course of cholangitis in the presence of biodigestive anastomoses popup.stage_title Head Smachylo Rostyslav M., Registration Date 08-01-2024 Organization State Institution "VT Zaitsev Institute of General and Emergency Surgery of the National Academy of Medical Sciences of Ukraine" popup.description2 The results of the research have shown that in patients with chronic wave-like cholangitis, disorders of the humoral component of the immunological response dominate. This is especially evident in patients who have already undergone reconstructive interventions on the biliary system but have not got rid of cholangitis, which occurs as a result of the launch of autoimmune reactions that cause immune-mediated destruction of hepatocytes and cholangiocytes, the consequences of these processes begin to decisively destroy the functional state of the liver and reparative processes in the area of biliodigestive anastomoses Product Description popup.authors Agarkova Alla Mykolayivna Bychenko Kateryna O. Drozdova Larissa Anatoliyivna Klyosova Maria O Lavinska Olena V Maloshtan Oleksandr V Neklyudov Andriy Oleksandrovich Smachylo Rostyslav M. popup.nrat_date 2024-01-08 Close