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Information × Registration Number 0224U000892, 0122U001205 , R & D reports Title To study clinical, functional and structural-morphological patterns of bronchopulmonary system damage in victims of the Chernobyl accident in the remote post-accident period and to determine the risks of complications popup.stage_title Head Shvaiko Liudmyla I., Доктор медичних наук Registration Date 14-01-2024 Organization State Institution "National Research Centre For Radiation Medicine of National Academy of Medical Sciences of Ukraine" popup.description2 Report: 88 p., 4 figures, 16 tables, 1 scheme, 64 sources, 2 appendices. The object of the study: the bronchopulmonary system state of persons who suffered of the Chernobyl NPP accident. Comprehensive prospective clinical and functional pulmonological study of 35 people who suffered of the Chernobyl NPP accident, and 10 people of the nosological control group (NC). The aim of the study: to carry out a clinical, functional and X-ray of COPD patients and to provide a comprehensive assessment of the bronchopulmonary system state in persons who suffered of the Chernobyl NPP accident. Research methods: generally clinical and laboratory examination, lung functional tests, lung CT, sleep apnea-hypopnea and night desaturation index analysis, lung ultrasound, informational and statistical. According to the comprehensive prospective clinical and functional study of the bronchopulmonary system of 35 liquidators of the Chernobyl NPP and 10 people of the NC, 12 patients of the military forces, a greater expressiveness of the inflammatory process by clinical signs was found, compared to the NC, a decrease in tolerance to physical exertion against the background of an increase of the reserve lung volumes and a decrease in the diffusion lung capacity. In clean-up workers at the Chernobyl NPP, the combination of COPD with obstructive sleep apnea (OSA) was associated with a greater number of COPD symptoms according to the CAT score (p = 0.007), a higher BMI and lower smoking intensity compared to COPD patients without OSA. Changes in the lung volume (decrease of the inspiratory capacity; increase of the intra-thoracic gas volume and residual lung volume) in COPD patients of the military forces, indicated the lung hyperinflation. OSA syndrome was detected in 36.3% of COPD patients of the main group, in 25% of the NC, and in 8.3% of patients of the military forces. Product Description popup.authors Bazyka Kostiantyn D. Sushko Viktor O. Shvaiko Liudmyla I. Shylenko Mariia V. popup.nrat_date 2024-01-14 Close