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Registration Number

0224U001001, 0122U001146 , R & D reports

Title

Development of a screening system for early diagnosis of cardiovascular diseases and COVID-19 based on rheographic research method

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Head

Sergeev Victor , Кандидат технічних наук

Registration Date

16-01-2024

Organization

O.M. Beketov national university of urban economy in Kharkiv

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A new technique for performing a test with an endothelium-independent vasodilator has been proposed. An analysis of the features of performing this test and data processing was carried out in accordance with the proposed information parameter and the influence on it of possible natural changes in the parameters of the CG and SCRTS. An algorithm for processing test data and a medical technique for conducting this research test have been developed. A functioning hardware and software complex for non-invasive assessment of endothelial function for large-scale screening examinations of the population has been developed and created. For the created complex, a medical research technique has been developed using tests with endothelium-dependent and endothelium-independent vasodilation of arterial vessels. Algorithms for automatic processing of recorded signals, algorithms for neutralizing changes in CG and SCRTS parameters, calculating the dynamic range of vascular tone regulation and recalculating the measurement result to the standard point of endothelial regulation have been developed. The software of the complex was developed and tested and instructions for its use were developed. Using the created hardware and software complex, more than three hundred experimental investigations were carried out, which fully confirmed the advantages of the proposed method for assessing FE and the possibility of its use for large-scale screening examination of the population. The proposed method allows screening examinations of the population, improves the quality of early diagnosis of the state of the cardiovascular system, the quality of assessment of cardiovascular risks, which will contribute to the application of timely preventive measures, correction of FE and reduction of disability and mortality of the population from cardiovascular diseases and COVID-19.

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Ihor V. Biletskyi
Dotsenko Nataliia V.
Kyrychenko Olena L.
Kopytsya Mykola P.
Kulbashevska Tetiana V.
Pavlenko Polina О.
Plankovsky Serhiy І.
Sergeev Victor