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Information × Registration Number 0224U001348, 0121U100305 , R & D reports Title Endothelial dysfunction, hypercoagulation and microvascular thrombosis in COVID-19: implications for risk assessment, pathogenesis, and diagnosis popup.stage_title Head Korda Mykhailo M., Доктор медичних наук Registration Date 22-01-2024 Organization Ternopil National Medical University named after I. Gorbachevsky of the Ministry of Health of Ukraine popup.description2  Report on the GDR: 108 pp., 84 sources, 30 tables, 22 figures. Endothelial dysfunction, COVID-19, recovery period, ACE2, adhesion molecules, endocan, endothelin-1, cytokine status, adiponectins, obesity, comorbidity. The object of the study is the pathogenesis of endothelial dysfunction, hypercoagulation and vascular microthrombosis in patients who have recovered from COVID-19. The aim of the work is to establish the molecular mechanisms of the development of endothelial dysfunction, hypercoagulation and vascular thrombosis in persons who have contracted COVID-19 of varying degrees of severity, through a comprehensive study of the production of vasorelaxing and vasoconstrictor factors by endotheliocytes, the degree of damage to the vessel walls, the functional state of the endothelium, indicators characterizing the presence of coagulopathy and thrombophilia, parameters of the intensity of oxidative stress and, as a result, the development of recommendations for risk assessment and prevention and prognostic and diagnostic criteria for the development of thrombosis and endothelial dysfunction in patients with COVID-19. Product Description popup.authors popup.nrat_date 2024-01-22 Close