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Information × Registration Number 0224U032773, (0122U000035) , R & D reports Title Features of the formation of resistance in representatives of opportunistic pathogens in health and pathology popup.stage_title Особливості формування резистентності у представників умовно-патогенної флори в умовах здоров'я і патології Head Klymniuk Serhii I., д.мед.н. Registration Date 04-12-2024 Organization Ternopil National Medical University named after I. Gorbachevsky of the Ministry of Health of Ukraine popup.description1 Study of the peculiarities of the formation of resistance of opportunistic flora in patients with somatic and infectious pathology, optimization of treatment methods. popup.description2 The research report contains 227 pages, 13 tables, 48 ​​figures, 284 sources ANTIBIOTICS, RESISTANCE, CONDITIONALLY PATHOGENIC FLORA, OPPORTUNISTIC INFECTIONS, BIOFILMS The object of the study is multiresistant strains of conditionally pathogenic and pathogenic microorganisms isolated from patients with somatic and infectious pathologies. The purpose of the work is to study the features of the formation of resistance of representatives of conditionally pathogenic flora in patients with somatic and infectious pathologies, optimization of treatment methods. Research methods - clinical and anamnestic; statistical; microbiological: microscopic, bacteriological, serial dilution method, "well" method, disk-diffusion method for determining antibiotic sensitivity, identification and determination of antibiotic resistance using the Vitek-2 compact apparatus, phagocytic activity and percentage of phagocytization of multiresistant strains in order to establish the degree of pathogenicity, establish their sensitivity to ozonated water, determine the film-forming properties of multiresistant representatives of opportunistic flora. The tools used are: light microscope BIOLAM R-1, sets of antibiotic discs, nutrient media, reagent sets, bacteriological analyzer Vitek-2 compact, steam sterilizer Granum SPV-50, thermostats TC-1, TC-80, centrifuge Liston C 2204, centrifuge OPn-3, microscope tritsok.-analyzer Seo-ImageLab 7002853, microscope tritsok.-analyzer Micromed, personal computer. The novelty of the study is that for the first time the features of biofilm formation by different strains of microorganisms were studied with an assessment of the ability of the isolated strains to form biofilms after antibiotic therapy. Product Description popup.authors popup.nrat_date 2024-12-04 Close