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Information × Registration Number 0224U032865, (0122U000162) , R & D reports Title Pharmacological properties of drugs of natural and synthetic origin and molecular mechanisms of their implementation in the defeat of internal organs of infectious and non-infectious origin popup.stage_title Фармакологічні властивості лікарських засобів природного і синтетичного походження та молекулярні механізми їх реалізації при ураженні внутрішніх органів інфекційного та неінфекційного генезу Head Oleshchuk Oleksandra M., д.мед.н. Registration Date 09-12-2024 Organization Ternopil National Medical University named after I. Gorbachevsky of the Ministry of Health of Ukraine popup.description1 To establish molecular mechanisms of hepatoprotective action of L-ornithine L-aspartate, antimicrobial and oncoprotective action of extracts from shiitake, maitake and reishi mushrooms, influence of ACE inhibitors, ARA2 and beta-blockers on endothelial dysfunction and hypercoagulation; assess the impact of gender, age and education on the level of stress resistance in students in a pandemic in the process of distance learning. popup.description2  Research report: 72 pages, 97 sources. CCL4-INDUCED CIRRHOSIS, L-ORNITHINE-L-ASPARTATE, DMG-INDUCED CARCINOGENESIS, DRY EXTRACT FROM HOSTIA LANCETOLISTA, TESTOSTERONE-INDUCED BENIGN PROSTATE HYPERPLASIA, DRY EXTRACT FROM REICHI MUSHROOM, STRESS AND LOCKDOWN CAUSED BY COVID-19, SUCCINIC ACID Object of the study - pharmacological properties of the action of L-ornithine-L-aspartate in CCL4-induced cirrhosis, extract from hosta lanceolate leaves in carcinogenesis induced by 1,2-dimethylhydrazine, dry extract from reishi mushrooms in testosterone-induced benign prostatic hyperplasia; the impact of stress and lockdown caused by COVID-19 on foreign higher education students who were in isolation; immunobiological properties of succinic acid; acute toxicity of dry extract from Sakhalin grass rheinnutria. The aim of the work is to investigate the effectiveness of L-ornithine-L-aspartate (LOLA) under conditions of blockade of nitric oxide and polyamine synthesis, the anti-inflammatory properties of dry extract from hosta lanceolate leaves in an experiment on rats with chemically induced cancer, dry extract from reishi mushrooms on the development of inflammatory processes in rats with testosterone-induced prostatic hyperplasia; to investigate the impact of stress and lockdown caused by COVID-19 on the mental health and well-being of foreign students, the properties of succinic acid, the safety of dry extract from Sakhalin grass rheinnutria. Product Description popup.authors popup.nrat_date 2024-12-09 Close