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Information × Registration Number 0225U000212, (0123U101772) , R & D reports Title Science-based concept of control measures and innovative means of prevention of biological threats to ensure national security popup.stage_title Апробація та впровадження у виробництво біоцидів, що руйнують біоплівки мікроорганізмів та імуномодуляторів для кореляції імунної тварин Head Fotina Tetiana I., д.вет.н. Registration Date 07-01-2025 Organization Sumy National Agrarian University popup.description1 To monitor the causative agents of infectious diseases on the territory of Ukraine in war and post-war times and to develop a system of control and prevention of bacterial diseases of animals as a prevention of epidemics caused by zoonoses, which will allow predicting the possible impact of the introduction of the disease, determining the probability of biological and economic consequences of its fixation, spread and spread and to develop adequate countermeasures according to the concept of "One Health" and "Strategy of biosafety and biological protection". popup.description2 Production trials of the new biocide "Sukhodez" were conducted in facilities for floor-raised poultry. A reduction in the number of bacteria, microscopic fungi, and Eimeria oocysts was observed. The hygroscopic properties of the biocide "Sukhodez" were confirmed. The ban on the use of antimicrobial agents as growth stimulators and for the prevention of bacterial infections has led to the search for alternative preventive measures. A production experiment was conducted using probiotic bacterial strains to prevent bacterial infections in broiler chickens, rabbits, and pigs. It was found that probiotics inhibited the growth and reproduction of pathogenic microflora in the intestines, allowing them to be added to animal diets as growth stimulators and biocides. The use of probiotics in lactating cows with ketosis contributed to the restoration of metabolism, productivity, and the reduction of ketone levels. Control measures were developed to prevent the spread of ectoparasites and bacterial infections in carp before their release into water bodies. After treatment with the iodine-containing product "Kombiyod," a reduction in contamination by microorganisms and ectoparasites was observed. In the search for a natural and effective component to eliminate microorganisms, research was conducted using high-performance liquid chromatography (HPLC) on eight varieties of Lonicera japonica. The content of phenolic acids in the leaves and branches of the plants was determined. Results were evaluated using multivariate statistical methods such as cluster analysis, comprehensive factor analysis, and partial least squares discriminant analysis (PLS-DA). PLS-DA identified chlorogenic acid, caffeic acid, and ferulic acid as the main components influencing the phenolic acid content in the plants. Antimicrobial peptides can regulate gut microbiota and maintain intestinal homeostasis. Product Description popup.authors Berezovskyi Andrii V. Petrov Roman V. Fotina Hanna A. Shkromada Oksana I. popup.nrat_date 2025-01-07 Close