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Information × Registration Number 0225U000287, (0124U003764) , R & D reports Title Design of composite biomaterials with special properties for medical application popup.stage_title Синтез та дослідження композитів легованих мікроелементами кальцій фосфатів з оксидом цирконію Head Nataliia Y. Strutynska, Доктор хімічних наук Registration Date 08-01-2025 Organization Taras Shevchenko National University of Kyiv popup.description1 Design of composite biomaterials with special functional characteristics (mechanical resistance, antimicrobial action and magnetic properties) based on doped calcium phosphates by trace elements and oxides of zirconium, silicon or ferrites of divalent metals, their characterization by physicochemical methods, in vitro testing and formulation of recommendations for further implementation preclinical research and introduction of materials with the best characteristics into medical practice. popup.description2 Today, the search for effective materials for bone tissue restoration is extremely relevant. Including such materials are needed by military and civilian medicine in the treatment of traumatic bone injuries, filling defects after removal of damaged areas and in other cases. The purpose of the research is to create composite biomaterials with special functional characteristics (mechanical resistance, antimicrobial action and magnetic properties) based on calcium phosphates doped with trace elements and zirconium oxides, silicon or ferrites of divalent metals, their characterization by physicochemical methods, in vitro testing and formulation of recommendations for further preclinical studies and the introduction of materials with the best characteristics into medical practice. The main objectives of the Project: 1. To develop synthesis methods for doping calcium phosphates (apatite type and TCP) with trace elements (sodium, potassium, zinc, etc.), and other cations and anions. 2. To develop methods for one-step synthesis of composite materials based on various forms of doped calcium phosphates and zirconium or silicon oxides or ferrites of divalent metals. 3. To investigate the influence of the phase composition of composites on their mechanical characteristics. 4. Investigation of the bioactivity, antimicrobial properties, cytotoxicity, and hemocompatibility of the developed composites. Assess the prospects for their practical use for filling bone tissue defects or its restoration for orthopedics and dentistry. Formulate recommendations for further preclinical research and the introduction of materials with the best characteristics into medical practice.  Product Description popup.authors Hryniuk Iryna І. Dremova Lidiia D. Komashchenko Yeva O. Livitska Oksana V. Prokhorenko Dmytro С. popup.nrat_date 2025-01-08 Close