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Information × Registration Number 0225U000423, (0121U114618) , R & D reports Title To develop the practice of treatment of clinical variants of megaureterer in children of younger age groups with the use of minimally invasive methods popup.stage_title Розробити тактику лікування клінічних варіантів мегауретера у дітей молодших вікових груп із застосуванням малоінвазивних методів Head Peterburhskyi Volodymyr F., д.мед.н. Registration Date 11-01-2025 Organization State Institution "Academician O.F. Vozianov Institute of Urology of the National Academy of Medical Sciences of Ukraine" popup.description1 Тo develop a concept for the tactics of management of young children with megaureter in order to improve the quality of treatment. popup.description2  Objective: To develop principles for the selection of tentatively personalized tactics for the treatment of various clinical variants of megoureter in young children by analyzing the effectiveness of: a) endoscopic techniques (ureteral stenting for nonrefluxing megoureter (NRMU), correction of refluxing megoureter (RMU)); b) ureterocutaneostomy and c) conservative and observational approach. Subjects: young children with nonrefluxing and refluxing megaureter treated with minimally invasive methods. Results: The criteria for choosing the tactics of treatment of various variants of NRMU, which are the degree of upper urinary tract dilatation (UUTD), the activity of the microbial inflammatory process and the assessment of the functional state of the kidney, taking into account the age-related anatomical features of the bladder in children of the first years of life, were determined; The role and possibility of using ureteral stenting in children with NRMU as a palliative temporary approach in the treatment of this defect are revealed; Indications for the use of ureteral stenting in children with NRMU are formulated depending on the degree of dilatation of the UUTD and the activity of the microbial inflammatory process; The data on the effectiveness of conservative and observation tactics of management of children with NRMU in the absence of microbial inflammation have been finalized; Based on the evaluation of the effectiveness of various options - conservative and observation, endoscopic stenting of the ureter in NRMU, endoscopic correction in RMU, ureterocystoneostomy, ureterocutaneostomy - the tentatively personalized tactics of treatment of various clinical variants of megoureter in children of the younger age group have been substantiated; The enzymatic features of the metabolic reaction of the tubular apparatus of the renal parenchyma depending on the degree of suppression of the urodynamics of the UUT and options for minimally invasive treatment of megoureter. Product Description popup.authors Zarzhytska Liudmyla L. Kalinina Nataliia A. Kalishсhuk Oles A. Myhal Liudmyla Ya. Nikulina Halyna H. Peterburhskyi Volodymyr F. Poroshyna Tetiana V. Savchenko Viktoriia S. Serbina Iryna Ye. Shukaliuk Liudmyla E. popup.nrat_date 2025-01-11 Close