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Information × Registration Number 0225U000470, (0122U001456) , R & D reports Title Antagonistic and synergistic relationships in microbial associations popup.stage_title Антагоністичні та синергетичні взаємовідносини в мікробних асоціаціях Head Skliar Tetiana V., Кандидат біологічних наук Registration Date 12-01-2025 Organization Oles Honchar Dnipro National University popup.description1 Research of antagonistic and synergistic relationships in microbial associations. popup.description2 Object - microbial associations of the environment and the human body. The purpose of research is to investigate the antagonistic and synergistic relationships in microbial associations. Modern microbiological (methods of microscopic analysis, bacteriological methods) and complex methods for determining the antagonistic activity of microorganisms, methods of mathematical statistics were used in the research process. During the research, the antagonistic activity of probiotic strains Bifidobacterium bifidum №1 and Lactobacillus rhamnosus GG was first investigated against isolates of opportunistic bacteria isolated from the human gastrointestinal tract in dysbiotic disorders: representatives of the Enterobacteriaceae family and methicillin-resistant strains of Staphylococcus aureus. For the first time, the quantitative composition of the nutrient medium for deep cultivation of the Trichoderma sp. strain isolated from the soil was optimized, which is promising for the creation of biological preparations for plant protection against pathogens. Based on the obtained research results, the methods for studying the inhibitory effect of lacto- and bifidobacteria on opportunistic bacteria isolated from the gastrointestinal tract and the method for selecting the quantitative composition of the nutrient medium for deep cultivation of Trichoderma sp. were modified. A comprehensive method for protecting ""Muscatny"" pumpkins from fungal diseases: anthracnose and downy mildew, based on the combined use of Trichoderma sp. and the chemical fungicides ""Cabrio Duo"" and ""Topsin M"", has been developed. An innovative product created as a result of scientific work can be used in the system of plant protection against mycoses in the agricultural sector of Ukraine. Product Description popup.authors Vorobiei Yelyzaveta S. Havryliuk Viktoriia H. Drehval Oksana A. Zubareva Inna M. Kurahina Nina V. Lavrentieva Kateryna V. Lykholat Tetiana Yu. Skliar Tetiana V. popup.nrat_date 2025-01-12 Close