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Information × Registration Number 0225U000559, (0124U001939) , R & D reports Title Study of the persistence of genomic instability induced by malignant cells of the A-549 line during the development of primary and secondary radiation-induced bystander effect in human somatic cells popup.stage_title Дослідження персистенції геномної нестабільності при розвитку пухлинно-індукованого ефекту свідка в соматичних клітинах людини. Head Shemetun Olena V., Доктор медичних наук Registration Date 14-01-2025 Organization State Institution "National Research Center for Radiation Medicine, Hematology and Onkology of the National Academy of Medical Sciences of Ukraine" popup.description1 To determine the nature and cytogenetic criteria of the persistence of genomic instability induced by malignant cells of the A-549 line during the development of the primary and secondary radiation-induced bystander effect in human somatic cells. popup.description2 Object: human peripheral blood lymphocytes; culture of human non-small-cell lung cancer cell line A549. Purpose: to investigate the persistence of genomic instability during the development of tumor-induced bystander effect in human somatic cells. Method: cytogenetic. Results: the persistence of genomic instability during the development of tumor-induced bystander effect in human peripheral blood lymphocytes during cultivation with conditioned medium from human non-small cell lung cancer cells of the A-549 line during four cell divisions was established, which was characterized by an increase in the frequency of single fragments. Product Description popup.authors Yeremieieva Mariia M. Velychko Svitlana V. Dybska Olena B. Talan Oksana O. popup.nrat_date 2025-01-14 Close