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Information × Registration Number 0225U002156, (0122U000334) , R & D reports Title Optimize methods of diagnosis and comprehensive treatment of tumors of the chiasmal-selar area popup.stage_title Оптимізувати методи діагностики та комплексного лікування новоутворень хіазмально-селярної ділянки Head Huk Mykola О., д.мед.н. Registration Date 21-02-2025 Organization The State Institution "Romodanov Neurosurgery Institute, National Academy of Medical Sciences of Ukraine" popup.description1 Optimize the diagnosis and comprehensive treatment of tumors of the chiasmal-selar area by introducing modern methods of ophthalmic and neuroimaging diagnostics and improving surgical treatment using minimally invasive technologies; development of individualized approaches to complex adjuvant treatment based on the optimal amount of morphological, immunohistological and molecular genetic studies popup.description2  Report on the GDR: 43 pp., 5 tables, 35 sources. TUMORS OF CHIASMAL-SELLAR LOCATION, PITUITARY ADENOMAS, CRANIOPHARYNGIOMAS, MENINGIOMAS, OPTICAL COHERENCE TOMOGRAPHY, IMMUNO-HISTOCHEMICAL STUDY. Changes according to optical coherence tomography in patients with tumors of chiasmal-sellar localization were studied. The effectiveness of this method for establishing early indications for surgical treatment of patients with neoplasms of the chiasmal-sellar region has been proven. A classification of the severity of chiasmal syndrome was developed and implemented in clinical practice: the severity of chiasmal syndrome was assessed taking into account the visual acuity and field of vision (according to the total loss of light sensitivity - MD) in both eyes: mild chiasmal syndrome (visual acuity 1.0 in both eyes, MD up to -4 dB); moderate chiasmal syndrome (visual acuity above 0.1 in both eyes, MD from -4 dB to -12 dB); severe (visual acuity less than 0.1, at least in one eye, MD> -12 dB, at least in one eye). A classification of the spread of giant pituitary adenomas into the ventricular system has been developed and implemented into clinical practice, which allows determining the volume and necessity of plastic surgery of the postoperative defect at the preoperative stage. The classification is based on the data of MRI and MSCT studies (with intravenous contrast), which indicate the involvement of the ventricular system in giant pituitary adenomas. Type 0 - no interaction with the ventricles of the brain, 1 - adherence to the ventricles (3 and lateral) with their compression or deformation, 2 - spreading into the ventricular cavity, 3 - spreading into the ventricular cavity with blockage of the foramen of Monro and/or hydrocephalus. A methodology for scoring the quality of life of patients with hormonally inactive pituitary adenomas has been developed and implemented, in which an author's series of nosologically-specific indicators accepted for research: ophthalmologica Product Description popup.authors Yehorova Kateryna S. Huk Mykola O. Musulevska Valeriia V. Solovei Mar'iana L. Ukrainets Oleksii V. Tsiurupa Dmytro M. Chernenko Oksana H. Chuvashova Olha Yu. Chukov Andrii A. popup.nrat_date 2025-02-21 Close